Professor Giulio Alessandri-Bonetti graduated in Medical Sciences (MD) followed by a postgraduate degree in Dental Sciences (DDS) at the University of Bologna, Italy. He received his postgraduate training in orthodontics at the University of Ferrara, Italy. He became Assistant Professor at the University of Bologna in 2005. Since 2015 he has been Associate Professor and Chairman of the Department of Orthodontics and Dean of the School of Dental Hygiene.
He has authored or co-authored more than 120 research papers and book-chapters. In 2012 received the David L. Turpin Award for Evidence-Based Research
from the American Journal of Orthodontics and Dentofacial Orthopedics. He is currently a member of the Italian Society of Orthodontics, the European
Orthodontic Society, the American Association of Orthodontists and the International College of Dentistry.
Oral appliances for obstructive sleep apnoea: an evidence-based analysis.
This lecture will focus on the management of obstructive sleep apnoea (OSA) with mandibular advancement devices (MADs). MADs are removable orthodontic devices which protrude the mandible and increase the upper airway patency during sleep thereby diminishing the upper airway collapsibility and elevating upper airway muscle tone. They are increasingly used to treat mild to moderate OSA and those patients with severe OSA who prefer to avoid, or are not appropriate candidates, for continuous positive airway pressure therapy or surgery. This presentation will explore the current status of research in the field.
The following topics will be discussed: cephalometric predictors of treatment outcome, effectiveness of different mandibular advancement amounts, dentoskeletalchanges after long-term and continuous MAD wear.
Mauro Farella is Professor and Chair of Orthodontics at the University of Otago, New Zealand, where he also serves as Associate Dean of Postgraduate Studies, Director of the Postgraduate Programme in Orthodontics, and Director of the Research Programme in Craniofacial Biology and Clinical Oral Physiology. He holds a DDS Degree (University of Naples, 1993), a PhD in Oral Sciences (University of Reggio Calabria, 1999), a Specialist Degree in Orthodontics (University of Naples, 2002), a Specialist Degree in Medical Statistics (University of Milan, 2007), and the "Venia Legendi" in Switzerland (University of Zürich, 2009). He is also a Certified Member of the European Board of Orthodontists .
His current research interests include craniofacial growth, clinical research, and biomechanics in orthodontics. Professor Farella is a widely recognized expert in jaw function, bruxism, and temporomandibular joint research. He has published more than 120 original articles in peer-reviewed international journals. He has served on the Editorial Board of the Journal of Dental Research, and is currently serving in that capacity on the Journal of Oral Rehabilitation. He lectures worldwide and is an active member of many associations. He is the recipient of several national and international research prizes acknowledging excellence achieved in dental research; these include the Alan Docking Award from the International Association for Dental Research and the Sir John Walsh Award.
Snapshots of orthodontic gnathology: the facts from the fiction
Orthodontic treatment often follows gnathologic principles to achieve an ‘optimal’ or ‘ideal’ occlusion and jaw relationship. Often these concepts are
related to function/dysfunction of the masticatory system and are considered as an indication for orthodontic treatment. However, they are not substantiated
by reliable scientific evidence. This is the case also for several claims such as that a good occlusion is important for biting, chewing, speaking,
swallowing, and breathing, and that occlusal anomalies in the form of crossbites or a Class II jaw relationship can be risk factors for temporomandibular
disorders and/or sleep disordered breathing.
This lecture will review gnathologic aspects of orthodontics in an attempt to distinguish fact from fiction around the relationship between occlusal anomalies and jaw function or dysfunction and will endeavour to answer the following questions. What is a good occlusion? Is a good occlusion important for correct jaw function? Are the classic gnathologic principles still relevant to modern orthodontics? What are the red flags to consider before, during or after orthodontic treatment?
The lecture will also address the emerging evidence indicating that the risk of non-adaption to occlusal changes depends more upon neurocognitive aspects than the type or severity of occlusal anomaly.
Professor Piotr Fudalej studied dentistry at Warsaw Medical University and biology at the University of Warsaw. He completed a postgraduate orthodontic programme at the University of Washington, Seattle, USA. He has a PhD degree from Radboud University Medical Center, Nijmegen, Netherlands. Currently, he is affiliated with Palacky University Olomouc, Czech Republic and the University of Bern, Switzerland. His main research areas are: effects of orthodontic treatment on periodontal health and cleft lip and palate. Both research lines have been in collaboration with Radboud University Medical Center, Nijmegen. He received the 2010 Samuel Berkowitz Long-Term Outcomes Study Award for the best long-term outcomes study published in 2009 in the Cleft Palate-Craniofacial Journal. He has published more than 80 scientific papers in peer-reviewed journals.
Biotype and the development of gingival recession in orthodontic patients.
Can Orthodontics Be Accelerated?
The Index of Orthognathic Functional Treatment Need
Dr Greg Huang received his dental degree from the University of Florida (1987), and then earned a Certificate in Orthodontics and an MSD from the University
of Washington (1989). After 10 years of private practice, he decided to pursue an academic career and accepted a faculty position at the University
of Washington where, concurrently, he also enrolled in the MPH program in epidemiology. On
completion of his MPH in 2001, he began his career as a clinical scientist, and has been involved with many studies, from retrospective investigations to randomized trials. He is a well-known advocate of evidence-based orthodontics, lecturing nationally and internationally on this topic. In 2008, he was named Chair of the Department of Orthodontics at the University of Washington.
Dr Huang is a Diplomate of the American Board of Orthodontics, as well as an Angle Society member. He has published more than 70 articles, and is the co-editor of two orthodontic textbooks: Evidence-based Orthodontics (2011) and
Orthodontics: Current Principles and Techniques, 6th edition (2016). He serves on the Editorial Boards of Orthodontics and Craniofacial Research and Journal of Orthodontics. He has also served as an Associate Editor for the American Journal of Orthodontics and Dentofacial Orthopedics.
Evidence-based methods have matured greatly over the past two decades, and the practice of orthodontics has benefited from the multitude of systematic reviews and meta-analyses that have been conducted. In this lecture, the 'evidence' in the context of vibration as an adjunct for faster tooth movement will be discussed. Several devices are commercially available, and many orthodontists are recommending vibration to their patients.
The existing evidence will be identified and assessed indicating the relative strength of studies based upon their design and conduct. The evidence will then be summarised and some recommendations provided for clinical practice. This lecture is intended to provide a real example of how evidence can be used by practitioners in their everyday interactions with patients - the ultimate goal of evidence-based orthodontics.
John Morton has over 25 years of experience in orthodontic biomechanics. Throughout his career, he has worked to improve orthodontic treatment by advancing
the understanding and application of biomechanical principles. He has previously held positions as Director of Research in the Department of Orthodontics
at the University of Connecticut and as a consultant for the NIH, universities, and private industry. With funding from the NIH, he founded OrthoMeasurements,
Inc., a company dedicated to designing and manufacturing orthodontic force and moment measuring instruments for intraoral use.
The authors of the following abstract have indicated a financial interest.
Control of Treatment with the Invisalign System
Dr Manuel Roman received his Bachelor´s Degree in Dentistry from the European University in Madrid and his Master of Orthodontics and Dentofacial Orthopedics from the University of Southern Mississippi, Institution of Spain.
He is the Director of the Masterof Orthodontics at UAH in Madrid, as well as European Master of Aligners and Latin American Aligners Institute in more than 30 countries. He has also taught under- and postgraduate courses at a number of universities. Dr Roman is a Key Opinion Leader, clinical speaker for Align Technologies and a member of the Advisory Board of Invisalign. He is a national and international speaker and has presented Invisalign G3, G5 and G6 in Spain together with various other presentations. He is a diamond provider having treated more than a 1500 patients.
Currently, Dr Roman combines his scholarly expertise with his orthodontic private practice in Malaga, Spain.
Control of Treatment with the Invisalign System
Dr Mujagic has had a private practice in Paris, France, since 1996. She specializes in lingual orthodontics and, in 2006, limited her practice to that
specific treatment approach.
Completely customized lingual orthodontics for adults and adolescents: beyond tooth alignment
Psychological aspects of orthodontic malocclusions
A closer look at life-long retention
Most orthodontists believe that a truly stable treatment outcome is a myth and that maintaining ideal alignment can only be achieved with some kind
of permanent retention. Preserving incisor alignment is especially important from the patient’s perspective and, for this reason, an increasing
number of orthodontists advocate life-long retention.
David Rice is Professor and Head of Orthodontics at the University of Helsinki and Helsinki University Hospital, and Director of the Finnish National Doctoral Programme in Oral Sciences. He specialised in orthodontics in the United Kingdom completing his PhD in craniofacial developmental biology in Finland.
His research is aimed at understanding the aetiology of craniofacial anomalies such as craniosynostosis and cleft lip and palate. He has published in some of the top journals including Development, Journal of Clinical Investigation and Human Molecular Genetics. His distinctions include both the Houston Research Award and Scholarship from the European Orthodontic Society, the Sulo Toivanen Award (Best PhD Thesis) from the Finnish Cell and Developmental Biology Society, an Honorary Fellowship from the Royal College of Surgeons of Edinburgh, and Research Fellowships from the Wellcome Trust UK and the Medical Research Council UK. Professor Rice is Editor of the European Journal of Orthodontics
Breakthroughs in understanding cleft lip and palate and craniosynostosis: implications for treatment and for orthodontics
I will review some of the dramatic recent advances that have been made in understanding the aetiology of craniofacial anomalies. The normal development of the craniofacial region, including the lips, palate and bones, will be described emphasising the critical stages and the key regulatory mechanisms that can go wrong and result in a craniofacial deformity.
Focusing on cleft lip and palate and craniosynostosis, laboratory examples will be given on how new technologies are being used to unravel the mechanisms of disease. The seemingly insurmountable limitations of correcting the causes of developmental abnormalities that occur before birth will also be described; in addition how understanding the aetiology and characteristics of a developmental condition can be of great benefit to patients.
Dr Maisa Seppala (DDS, MSc, PhD, MOrthRCSEd, FDSOrthRCSEng, FHEA) is a clinical lecturer in orthodontics at King’s College London (KCL) based at Guy’s and St Thomas’ NHS Foundation Trust. She graduated as a dentist in 2002 at Oulu Dental Institute, Finland and undertook a PhD in the Department of Craniofacial Development at KCL. This project, focussed on the regulation of Sonic hedgehog (Shh)signalling by the transmembrane protein Gas1 during craniofacial development. Her research introduced Gas1 as a potential causative gene for the significant human malformation Holoprosencephaly. She has subsequently further investigated the role of genetic modifiers associated with this condition and her current research focuses on how Gas1 regulates dental formula by interacting with Shh and other possible novel signaling pathways. Following her PhD she undertook orthodontic specialist training at KCL, which was followed by an NIHR funded Academic Clinical Fellowship and accreditation as a Consultant Orthodontist.
Searching for the molecular causes of altered tooth number in mouse and man
Development of the dentition is a well-coordinated process, where multiple novel molecular pathways function together to provide the right number of
teeth at the right time and in the right place. Sonic Hedgehog (Shh) is a secreted signalling molecule that plays a crucial role during early tooth
development by inducing proliferation, cell polarisation and by establishing an appropriate morphogenic gradient during cuspal patterning. In the
mouse, defective Shh signalling can result in incisor and molar fusion, whilst over-activity has been associated with supernumerary tooth formation.
In human populations, aberrant Shh signalling can induce a variety of craniofacial anomalies, including maxillary incisor fusion and midline facial
defects. Similarities in mammalian and human genomes and disease phenotypes enable investigation into the causes of tooth anomalies with advanced
molecular techniques, powerful genome sequencing methods and bioinformatics.
This presentation will discuss how genetic screening studies have enabled clinicians to identify new candidate genes associated with variable dental anomalies and how the underlying molecular mechanisms can be further explored by using the mouse as a developmental model.
Professor Guy Willems is the Chair of the Orthodontic Section of the Department of Oral Health Sciences and Programme Director of the combined Master/Clinical Postgraduate Training Programme in Orthodontics at the KU Leuven, Belgium.
Professor Willems completed his L.D.S. in 1988 and received his Ph.D. in 1992, both at KU Leuven, Belgium. He completed his orthodontic specialty training in 1996 and has been an academic and clinical staff member of the Orthodontics Section in Leuven since 1997. He is director of Ortholeuven, a centre for continuing education in the field of orthodontics for promotion of the KU Leuven Orthodontic Training Programme.
He has published extensively as an author and co-author and is an editorial board member of the European Journal of Orthodontics. His research interests and areas of expertise focus, among others, on oral health-related quality of life, canine impaction, resistance to sliding in orthodontics, dental age estimation, traumatized teeth and retention.
Does Orthodontic Treatment Improve a Patient's Quality of Life?
The silent revolution within general health has created a paradigm shift from a disease-centred into a patient-centred approach, generating aspects such as oral health-related quality of life (OHRQoL). According to the World Health Organization, health is a state of complete functional, psychological and social wellbeing. Good oral health is more than just absence of disease; the optimal physical, mental and social wellbeing of our patients, is the ultimate focus of our daily practice and research.
In the past, the concept of improving quality of life through orthodontic treatment focused on discomfort, functional problems with eating or speaking and on creating a beautiful smile. Nowadays, the focus does not just concern the oral cavity but the person as a whole, requiring a more subjective, patient-based approach. A person’s OHRQoL is indeed defined by the influence of functional (chewing and speaking, current and past experiences), psychological (appearance and self-esteem), and social aspects (communication, social interaction, intimacy) as well as by a person’s background and cultural upbringing.
This biopsychosocial approach to oral health care requires further investigation to better understand the patient’s expectations and the possible role of malocclusion treatment on function and psychosocial well-being. Numerous investigations are being organized at various phases of orthodontic treatment employing validated scales and questionnaires for this specific purpose. The focus of these long term prospective clinical trials is primarily concentrated on the effect of orthodontic treatment on the OHRQoL both in children and adults, and the possible moderating role of personality traits and self-esteem. Adjunct information may be obtained through gauging the patient’s motivation for treatment and the correlation between their expectations and the final treatment results.